South African President, Jacob Zuma, is facing yet another threat to his presidency with a renewed call by three of his cabinet members for him to stand down.

Derek Hanekom, the Minister of Tourism, was the first to raise a motion in the country’s ruling ANC, calling for a vote of no confidence on the president.

Two other cabinet ministers are understood to be backing Hanekom’s proposal, they are: Health Minister, Aaron Motsoaledi and Public Works Minister, Thulas Nxesi.

President Zuma has survived several similar votes in the parliament but this is the first time the ANC will formally discuss his position.

Zuma has increasingly come under criticism over corruption allegations, with a recent report highlighting his links with the wealthy Gupta family.

Analysts say this could shape into the toughest battle of Zuma’s career.

Earlier this month, an investigation by the country’s anti-corruption watchdog said a judicial inquiry should be set up to further investigate allegations of criminal activity in Zuma’s government.

The investigation found evidence that the Guptas, a business family with links to Zuma, may have wielded undue political influence over the appointment of ministers.

Both Zuma and the Guptas have denied any wrongdoing.